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Purpura haemorrhagica : ウィキペディア英語版 | Purpura haemorrhagica Purpura haemorrhagica is a rare complication of equine strangles and is caused by bleeding from capillaries which results in red spots on the skin and mucous membranes together with oedema (swelling) of the limbs and the head. Purpura hemorrhagica is more common in younger animals.〔 ==Pathophysiology== Horses that develop purpura hemorrhagica usually have a recent history of strangles (infection with ''Streptococcus equi'' subsp. ''equi'') or vaccination (intramuscular or intranasal) for strangles. It is thought to be caused by an auto-immune reaction where antibodies against the ''S. equi'' M- or R-protein cross-react with proteins on endothelial cells. This results in vasculitis, leading to subsequent severe peripheral edema in the legs and ventral abdomen, as well as petechiation or ecchymoses over the mucous membranes. Purpura hemorrhagica can also rarely be seen after infection with ''S. equi'' subsp.''zooepidemicus'',〔 ''Rhodococcus equi'',〔 ''Corynebacterium pseudotuberculosis'' (causative agent of pigeon fever),〔 equine influenza virus, or equine herpes virus type 1, or without any apparent infection.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Purpura haemorrhagica」の詳細全文を読む
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